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FAK aa411-686 Recombinant Human Active Protein Kinase

Focal adhesion kinase (FAK), a non-receptor tyrosine kinase in the cytoplasm, couples with integrins and growth factor receptors to regulate cell adhesion, proliferation, migration, invasion, and metastasis. FAK is overexpressed and aberrantly activated in many cancer types, including triple negative breast cancer (TNBC) . FAK aa411-686 Recombinant Human Active Protein Kinase is a recombinant FAK aa411-686 protein that can be used to study FAK aa411-686-related functions[1].

Product Specifications

UNSPSC

12352211

Target

FAK

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

[FAKaa411-686RecombinantHumanActiveProteinKinase]

References & Citations

[1]Zhang Y, et al. LncRNA FAISL Inhibits Calpain 2-Mediated Proteolysis of FAK to Promote Progression and Metastasis of Triple Negative Breast Cancer. Adv Sci (Weinh) . 2024 Nov;11 (42) :e2407493.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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