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EML4 ALK F1174L Recombinant Human Active Protein Kinase

EML4-ALK is a fusion-type protein tyrosine kinase produced through gene rearrangement. EML4-ALK can be used for the study of non-small cell lung carcinoma (NSCLC) and neuroblastoma (NB) . EML4-ALK has multiple mutants. EML4 ALK F1174L Recombinant Human Active Protein Kinase is a recombinant EML4 ALK F1174L protein that can be used to study EML4 ALK F1174L-related functions[1].

Product Specifications

UNSPSC

12352211

Target

Anaplastic lymphoma kinase (ALK)

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

[EML4ALKF1174LRecombinantHumanActiveProteinKinase]

References & Citations

[1]Guan J, et al. ALK F1174S mutation impairs ALK kinase activity in EML4-ALK variant 1 and sensitizes EML4-ALK variant 3 to crizotinib. Front Oncol. 2024 Jan 9;13:1281510.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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