EML4 ALK Recombinant Human Active Protein Kinase

EML4-ALK is a fusion-type protein tyrosine kinase produced through gene rearrangement. EML4-ALK is a potential molecular target in non-small cell lung carcinoma (NSCLC) . EML4 ALK Recombinant Human Active Protein Kinase is a recombinant EML4 ALK protein that can be used to study EML4 ALK-related functions[1].

Product Specifications

UNSPSC

12352211

Target

Anaplastic lymphoma kinase (ALK)

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

[EML4ALKRecombinantHumanActiveProteinKinase]

References & Citations

[1]Sun HY, et al. A molecular dynamics investigation on the crizotinib resistance mechanism of C1156Y mutation in ALK. Biochem Biophys Res Commun. 2012 Jun 29;423 (2) :319-24.