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CDK5/p25NCK Recombinant Human Active Protein Kinase

CDK5 can be mapped to chromosome 7q36 and its expression is upregulated by the transcription factors Fos and CREB through the MEK/ERK pathway and by δFosB. CDK5 plays a vital role in the central nervous system but has functions in other cell types. CDK5 has recently been implicated in diseases, including the development and progression of cancer and neurodegenerative diseases. CDK5/p25NCK Recombinant Human Active Protein Kinase is an ortholog of CDK5[1].

Product Specifications

UNSPSC

12352211

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer; Neurological Disease

Smiles

[CDK5/p25NCKRecombinantHumanActiveProteinKinase]

References & Citations

[1]Lavoie G, et al. Phosphorylation of human DNMT1: implication of cyclin-dependent kinases. Biochem Biophys Res Commun. 2011 Jun 3;409 (2) :187-92.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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