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CDK12/CycK Recombinant Human Active Protein Kinase

CDK12/CycK Recombinant Human Active Protein Kinase is a cyclin-dependent kinase that phosphorylates the C-terminal domain (CTD) of RNA polymerase II (Pol II), thereby regulating different phases of the transcription cycle from transcription initiation to elongation and termination[1].

Product Specifications

UNSPSC

12352211

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Smiles

[CDK12/CycKRecombinantHumanActiveProteinKinase]

References & Citations

[1]Bösken CA, et al. The structure and substrate specificity of human Cdk12/Cyclin K. Nat Commun. 2014 Mar 24;5:3505.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Frequently Asked Questions

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