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PIP5K1A Recombinant Human Active Lipid Kinase

PIP5K1A phosphorylates PI4P to synthesize the important signalling phospholipid PI (4,5) P2. This phospholipid also serves as the substrate for PI3K for conversion into PI (3,4,5) P3 to stimulate cell growth and survival. PIP5K1A has been directly implicated in breast cancer and prostate cancer. PIP5K1A Recombinant Human Active Lipid Kinase is a recombinant PIP5K1A protein that can be used to study PIP5K1A-related functions[1].

Product Specifications

UNSPSC

12352211

Target

PI3K

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

[PIP5K1ARecombinantHumanActiveLipidKinase]

References & Citations

[1]East MP, et al. PIP5K1A: a potential target for cancers with KRAS or TP53 mutations. Nat Rev Drug Discov. 2020 Jul;19 (7) :436.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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