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Dihydrofolate reductase

Dihydrofolate reductase is a key enzyme in folate metabolism and, therefore, in the production of thymidine. Its role in thymidine biosynthesis is the reduction of dihydrofolate to tetrahydrofolate using the cofactor NADPH[1].

Product Specifications

CAS Number

9002-03-3

Product Name Alternative

DHFR

UNSPSC

12352204

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

[Dihydrofolatereductase]

References & Citations

[1]Hongnan Cao, et al. The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol. 2018 Dec 12:1:226.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

No Development Reported

Frequently Asked Questions

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