Dihydrofolate reductase
Dihydrofolate reductase is a key enzyme in folate metabolism and, therefore, in the production of thymidine. Its role in thymidine biosynthesis is the reduction of dihydrofolate to tetrahydrofolate using the cofactor NADPH[1].
Product Specifications
CAS Number
[9002-03-3]
Product Name Alternative
DHFR
UNSPSC
12352204
Target
Others
Related Pathways
Others
Field of Research
Others
Smiles
[Dihydrofolatereductase]
References & Citations
[1]Hongnan Cao, et al. The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol. 2018 Dec 12:1:226.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Curated Selection
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