Rhodamine 123 (solution)

Rhodamine dyes are membrane-permeable cationic fluorescent probes that specifically recognize mitochondrial membrane potentials, thereby attaching to mitochondria and producing bright fluorescence, and at certain concentrations, rhodamine dyes have low toxicity to cells, so they are commonly used to detect mitochondria in animal cells, plant cells, and microorganisms[1].Solvent and concentration: DMSO: 5 mM

Product Specifications

CAS Number

[62669-70-9]

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Cardiovascular Disease

Smiles

O=C(C1=CC=CC=C1C2=C3C=CC(N)=CC3=[O+]C4=C2C=CC(N)=C4)OC.[Cl-]

Molecular Formula

C21H17ClN2O3

Molecular Weight

380.83

References & Citations

[1]M. Huang, et al. Mitochondrial Inner Membrane Electrophysiology Assessed by Rhodamine-123 Transport and Fluorescence. Ann Biomed Eng. 2007 Jul; 35 (7) : 1276–1285.|[2]Emaus, R. K., Grunwald, R., & Lemasters, J. J. (1986) . Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties. Biochimica et Biophysica Acta (BBA) - Bioenergetics, 850 (3), 436–448.