HADA (hydrochloride) (solution)
HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λem~450 nm) fluorescent D-amino acid (FDAA) . FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation[1].Solvent and concentration: DMSO: 50 mM
Product Specifications
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
N[C@H](CNC(C1=CC2=CC=C(O)C=C2OC1=O)=O)C(O)=O.[H]Cl
Molecular Formula
C13H13ClN2O6
Molecular Weight
328.71
References & Citations
[1]Erkin Kuru, et al. Synthesis of fluorescent D-amino acids and their use for probing peptidoglycan synthesis and bacterial growth in situ. Nat Protoc. 2015 Jan;10 (1) :33-52.|[2]Xu Q, et al. Phage protein Gp11 blocks Staphylococcus aureus cell division by inhibiting peptidoglycan biosynthesis. mBio. 2024 Jun 12;15 (6) :e0067924.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-DY1044/
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
CAS Number
[2253733-10-5]
Available Sizes
Curated Selection
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