Filipin complex (solution)
Filipin complex (solution) is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III , 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm)[2][3].Solvent and concentration: DMSO: 5 mg/mL
Product Specifications
CAS Number
11078-21-0
UNSPSC
12352211
Target
Antibiotic; Fungal
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
[Filipincomplex(solution)]
References & Citations
[1]Malcolm E. Bergy et al. Filipin complex. Biochemistry, 1968, 7, 2, 653-659.|[2]Houdai T, et al. Membrane-permeabilizing activities of amphidinol 3, polyene-polyhydroxy antifungal from a marine dinoflagellate. Biochim Biophys Acta. 2004 Nov 17;1667 (1) :91-100.|[3]Huang L, et al. Role of lipid rafts in porcine reproductive and respiratory syndrome virus infection in MARC-145 cells. Biochem Biophys Res Commun. 2011 Oct 28;414 (3) :545-50.|[4]Huang S, et al. Chimeric cerebral organoids reveal the essentials of neuronal and astrocytic APOE4 for Alzheimer's tau pathology. Signal Transduct Target Ther. 2022 Jun 13;7 (1) :176.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
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