Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

JC-1 (solution)

JC-1 (CBIC2) (solution) is an ideal fluorescent probe widely used to detect mitochondrial membrane potential. JC-1 accumulates in mitochondria in a potential dependent manner and can be used to detect the membrane potential of cells, tissues or purified mitochondria. In normal mitochondria, JC-1 aggregates in the mitochondrial matrix to form a polymer, which emits strong red fluorescence (Ex=585 nm, Em=590 nm) ; When the mitochondrial membrane potential is low, JC-1 cannot aggregate in the matrix of mitochondria and produce green fluorescence (ex=510 nm, em= 527 nm) [1].Solvent and concentration: DMSO: 1.5 mM

Product Specifications

CAS Number

3520-43-2

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Smiles

ClC1=C(Cl)C=C([N+](CC)=C(/C=C/C=C2N(C(C=C(Cl)C(Cl)=C3)=C3N\2CC)CC)N4CC)C4=C1.[I-]

Molecular Formula

C25H27Cl4IN4

Molecular Weight

652.22

References & Citations

[1]A Perelman, et al. JC-1: alternative excitation wavelengths facilitate mitochondrial membrane potential cytometry. Cell Death Dis. 2012 Nov 22;3:e430.|[2]Vera C. Keil, et al. Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria. Pflügers Archiv - European Journal of Physiology. 2011,462 (5) : 693-708.|[3]Jung-Ho LEE, et al. Real-time analysis of amyloid fibril formation of α-synuclein using a fibrillation-state-specific fluorescent probe of JC-1. Biochem. J. 2009, 418:311-323.|[4]Salvioli S, et al. JC-1, but not DiOC6 (3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett. 1997 Jul 7;411 (1) :77-82.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal Carm1 [p Ser228] Antibody
NBP3-16892-20ul 20 µL

Rabbit Polyclonal Carm1 [p Ser228] Antibody

Sign In for Pricing
View Details
ALDH1A1 (NM_000689) Human Recombinant Protein
E45H41852M5 20 µg

ALDH1A1 (NM_000689) Human Recombinant Protein

Sign In for Pricing
View Details
CD163 Rabbit Polyclonal Antibody (Fluoro647)
orb3081426 100 µg

CD163 Rabbit Polyclonal Antibody (Fluoro647)

Sign In for Pricing
View Details
CNN2 ELISA Kit (Human)
OKCD09196-96W 96 Well

CNN2 ELISA Kit (Human)

Sign In for Pricing
View Details
GOLGA6L4 Polyclonal Antibody, PE Conjugated
bs-13483R-PE 100 µL

GOLGA6L4 Polyclonal Antibody, PE Conjugated

Sign In for Pricing
View Details
Lentiviral human USP26 shRNA (UAS) - Lentiviral human USP26 shRNA (UAS) plasmid
GTR15159391 1 Vial

Lentiviral human USP26 shRNA (UAS) - Lentiviral human USP26 shRNA (UAS) plasmid

Sign In for Pricing
View Details