NpCy-4

NpCy-4 is a reliable reporter for monitoring lysosomal pH and viscosity changes in real time during Autophagy (λex = 650 nm; λem = 660-740 nm) . NpCy-4 demonstrates a superior signal-to-background ratio (SBR) for cellular imaging. NpCy-4 facilitates real-time, noninvasive diagnostic imaging of acute gastritis model with high contrast[1].

Product Specifications

UNSPSC

12352005

Target

Autophagy; Fluorescent Dye

Related Pathways

Autophagy; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(N(C1=O)CCN2CCOCC2)C3=C4C1=CC=CC4=C([N+](C)=C(/C=C/C(CCC5)=C6C5=CC(C=CC([O-])=C7)=C7O6)C8(C)C)C8=C3

Molecular Formula

C38H37N3O5

Molecular Weight

615.72

References & Citations

[1]Feng D, et al. pH-/Viscosity-Activatable NIR Fluorescent Probes via Acceptor Engineering of Hemicyanine Dyes for High-Contrast Bioimaging. Anal Chem. 2025 Feb 25;97 (7) :4041-4048.