ONOO-LysopH

ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes[1].

Product Specifications

CAS Number

[2567068-39-5]

UNSPSC

12352005

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Smiles

CCN1CCN(C2=C1C=C3OC4=C(C5(C6=C(C(N5N)=O)C=CC=C6)C3=C2)C=C7CCCN8CCCC4=C78)CC

Molecular Formula

C32H35N5O2

Molecular Weight

521.65

References & Citations

[1]Xia Q, et al. One probe for multiple targets: A NIR fluorescent rhodamine-based probe for ONOO− and lysosomal pH detection in live cells[J]. Sensors and Actuators B: Chemical, 2021, 337: 129732.