ONOO-LysopH
ONOO-LysopH is a new Rhodamine-based near-infrared fluorescent probe. ONOO-LysopH is acid-sensitive, exhibiting rapid near-infrared fluorescence enhancement around 686 nm under acidic pH conditions. ONOO-LysopH also displays a rapid NIR turn-on fluorescence around 678 nm for ONOO− at physiological pH. ONOO-LysopH can target lysosomes to track lysosomal pH changes and image endogenous/exogenous ONOO− in live cells. ONOO-LysopH is applicable for cell imaging ONOO− and tracking lysosomal pH changes[1].
Product Specifications
CAS Number
2567068-39-5
UNSPSC
12352005
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
CCN1CCN(C2=C1C=C3OC4=C(C5(C6=C(C(N5N)=O)C=CC=C6)C3=C2)C=C7CCCN8CCCC4=C78)CC
Molecular Formula
C32H35N5O2
Molecular Weight
521.65
References & Citations
[1]Xia Q, et al. One probe for multiple targets: A NIR fluorescent rhodamine-based probe for ONOO− and lysosomal pH detection in live cells[J]. Sensors and Actuators B: Chemical, 2021, 337: 129732.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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