ARHB

ARHB is a highly selective and sensitive NAT2 fluorescent probe suitable for real-time detection of NAT2 activity in various bacteria. ARHB can successfully penetrate the bacterial cells, and the fluorescence intensity is positively correlated with the expression level of NAT2. ARHB is used for high-throughput screening of natural inhibitors for tuberculosis[1].

Product Specifications

CAS Number

[2310262-15-6]

UNSPSC

12352005

Target

Fluorescent Dye; Histone Acetyltransferase

Related Pathways

Epigenetics; Others

Field of Research

Infection

Smiles

NC1=CC=C(C(C(C=CC(N(CC)CC)=C2)=C2O3)=C4C3=C/C(C=C4)=[N+](CC)\CC)C=C1.CC([O-])=O

Molecular Formula

C29H35N3O3

Molecular Weight

473.61

References & Citations

[1]Jin Y, et al. A highly selective fluorescent probe for real-time imaging of bacterial NAT2 and high-throughput screening of natural inhibitors for tuberculosis therapy[J]. Materials Chemistry Frontiers, 2019, 3 (1) : 145-150.