NCIC-VIS
NCIC-VIS is a lysosome-targeted, viscosity-sensitive two-photon near-infrared fluorescent probe. NCIC-VIS has a rigid structure that can restrict molecular torsion, thereby increasing the fluorescence quantum yield and two-photon absorption cross-section. NCIC-VIS enables real-time imaging of the autophagy process in cells[1].
Product Specifications
CAS Number
[2781892-92-8]
UNSPSC
12352005
Target
Autophagy; Fluorescent Dye
Related Pathways
Autophagy; Others
Field of Research
Neurological Disease
Smiles
CN(C)C1=CC(O2)=C(C=C1)C(N3CCOCC3)=C(/C=C/C(CC(C)(C)C/4)=CC4=C(C#N)/C#N)C2=O
Molecular Formula
C28H30N4O3
Molecular Weight
470.56
References & Citations
[1]Chai L, et al. Near-Infrared in and out: Observation of Autophagy during Stroke via a Lysosome-Targeting Two-Photon Viscosity-Dependent Probe. Anal Chem. 2022 Apr 19;94 (15) :5797-5804.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
Phase 3
Curated Selection
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