R-MA-SLM
R-MA-SLM is an Aβ-targeted and blood-brain barrier-permeable ratiometric H2O2-responsive fluorescent probe. When excited at 490 nm, the fluorescence intensity of the R-MA-SLM gradually decreases at 574 nm, while the emission intensity gradually increases at 661 nm. R-MA-SLM can detect and exhibits a ratiometric response to Aβ-induced endogenous H2O2. R-MA-SLM can be used in the research of Alzheimer's disease[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β; Fluorescent Dye
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(N(C1=CC=C(C=C1)/C=C/C2=C3C=CC=CC3=[N+](C)C=C2)C)OCC4=CC=C(B5OC(C)(C)C(C)(C)O5)C=C4.[I-]
Molecular Formula
C33H36BIN2O4
Molecular Weight
662.37
References & Citations
[1]Wang X, et al. Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer's Disease. ACS Appl Mater Interfaces. 2023 Jan 11;15 (1) :39-47.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
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