DAyne
DAyne is a Dopamine (DA) -mimetic probe. DAyne covalently binds to proteins modified by dopamine oxidation products (e.g., dopaquinone, DQ) to form adducts. DAyne is promising for research of Parkinson’s disease (PD), particularly neurotoxicity, protein modification, and related pathways (e.g., endoplasmic reticulum stress, cytoskeletal instability) caused by dopamine dysregulation[1].
Product Specifications
CAS Number
[1866495-46-6]
UNSPSC
12171500
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Neurological Disease
Smiles
OC1=C(O)C=CC(CCNCC#C)=C1
Molecular Formula
C11H13NO2
Molecular Weight
191.23
References & Citations
[1]Hurben AK, et al. Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonally Functionalized Catecholamine. ACS Chem Biol. 2021 Nov 19;16 (11) :2581-2594.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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