NFC nitro probe 1
NFC nitro probe 1 (compound 18) is an NFC termed probe for Mtb detection. NFC nitro probe 1 (compound 18) shows high potency for R-Mtb and NR-Mtb[1][2].
Product Specifications
CAS Number
1604838-69-8
UNSPSC
12171500
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection; Inflammation/Immunology
Smiles
CC1(C)OC2=C3C(OC(C=C3CCC)=O)=C4C(OC([N+]([O-])=O)=C4)=C2CC1
Molecular Formula
C19H19NO6
Molecular Weight
357.36
References & Citations
[1]Ana Negri, et al. Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis. ACS Infect Dis. 2018 May 11;4 (5) :771-787.|[2]Purong Zheng, et al. Synthetic calanolides with bactericidal activity against replicating and nonreplicating Mycobacterium tuberculosis. J Med Chem. 2014 May 8;57 (9) :3755-72.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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