TPE-PY

TPE-PY is a fluorescent dye targeting mitochondria, which has cationic and lipophilic characteristics, enabling specific targeting of mitochondria. TPE-PY functions through the aggregation-induced emission (AIE) mechanism. TPE-PY mechanism of action is based on the restriction of intramolecular rotation (RIR), which enhances fluorescence in the aggregated state. TPE-PY is mainly used in the field of biological imaging, especially for the specific staining of mitochondria in living cells, facilitating the observation of the location, morphology, and quantity of mitochondria[1].

Product Specifications

CAS Number

[3032077-04-3]

UNSPSC

12171500

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Metabolic Disease

Purity

99.67

Smiles

OCC[N+]1=CC=C(C=C1)/C=C/C2=CC=C(/C(C3=CC=CC=C3)=C(C4=CC=CC=C4)/C5=CC=CC=C5)C=C2.[Br-]

Molecular Formula

C35H30BrNO

Molecular Weight

560.52

References & Citations

[1]Zhao N, et al. A tetraphenylethene-substituted pyridinium salt with multiple functionalities: synthesis, stimuli-responsive emission, optical waveguide and specific mitochondrion imaging[J]. Journal of Materials Chemistry C, 2013, 1 (31) : 4640-4646.