H-FluNox

H-FluNox is a selective fluorescent probe that senses labile heme using biomimetic N-oxide deoxygenation to trigger fluorescence. H-FluNox is more than 100-fold selective for labile heme over Fe (II), enabling the discrimination of labile heme from labile Fe (II) pools in living cells. H-FluNox is sensitive enough to detect the subcellular labile heme. (λex=490 nm, λem=535 nm)

Product Specifications

CAS Number

[2897614-59-2]

UNSPSC

12171500

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Purity

99.53

Smiles

O=C1OC2(C3=C1C=CC=C3)C4=CC=C(C=C4OC5=CC([N+]6(CCC(F)(CC6)F)[O-])=CC=C52)O

Molecular Formula

C25H19F2NO5

Molecular Weight

451.42

References & Citations

[1]Kawai K, et al. Molecular Imaging of Labile Heme in Living Cells Using a Small Molecule Fluorescent Probe. J Am Chem Soc. 2022 Mar 9;144 (9) :3793-3803.