5-Carboxytetramethylrhodamine

5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm[1][2][3].

Product Specifications

CAS Number

[150322-05-7]

UNSPSC

12171500

Target

Fluorescent Dye

Related Pathways

Others

Field of Research

Others

Purity

99.13

Solubility

DMSO : 11.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC2=C(C3(C4=C(OC5=C3C=CC(N(C)C)=C5)C=C(N(C)C)C=C4)OC2=O)C=C1)O

Molecular Formula

C25H22N2O5

Molecular Weight

430.45

References & Citations

[1]Lyu Z, et al. Steric-Free Bioorthogonal Labeling of Acetylation Substrates Based on a Fluorine-Thiol Displacement Reaction. J Am Chem Soc. 2021 Jan 27;143 (3) :1341-1347.|[2]Bucevičius J, et al. Rhodamine-Hoechst positional isomers for highly efficient staining of heterochromatin. Chem Sci. 2018 Dec 12;10 (7) :1962-1970.|[3]Lyttle MH, et al. A tetramethyl rhodamine (Tamra) phosphoramidite facilitates solid-phase-supported synthesis of 5'-Tamra DNA. J Org Chem. 2000 Dec 29;65 (26) :9033-8.