EGTA (tetrasodium)
EGTA tetrasodium is a specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM) . EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2].
Product Specifications
CAS Number
13368-13-3
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Inflammation/Immunology
Purity
99.93
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O[Na])CN(CC(O[Na])=O)CCOCCOCCN(CC(O[Na])=O)CC(O[Na])=O
Molecular Formula
C14H20N2Na4O10
Molecular Weight
468.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Harris RA, Hanrahan JW. Effects of EGTA on calcium signaling in airway epithelial cells. Am J Physiol. 1994;267 (5 Pt 1) :C1426-C1434. doi:10.1152/ajpcell.1994.267.5.C1426.|[2]Segura-Egea JJ, Jiménez-Rubio A, Rios-Santos JV, Velasco-Ortega E, Calvo-Gutierrez JR. In vitro inhibitory effect of EGTA on macrophage adhesion: endodontic implications. J Endod. 2003;29 (3) :211-213.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC041398-500 1x 500 µL
BRCA1 (Breast Marker) (BRCA1/1398), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401832-100 1x 100 µL
Spectrin Alpha 1 (Erythrocyte Marker) (SPTA1/1832), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
H-8003-1 1 mg
HRP Conjugated Aegopodium podagraria Lectin (Ground Elder) -APP-
Sign In for Pricing
View Details 
