Gallein (Standard)

Gallein (Standard) is the analytical standard of Gallein. This product is intended for research and analytical applications. Gallein is a Gβγ subunit signaling inhibitor that can interfere with the interaction between Gβγ subunit and PI3Kγ, regulate platelet function, and exhibit anti-tumor activity[1][3].

Product Specifications

CAS Number

[2103-64-2]

UNSPSC

12352100

Target

PI3K; Reference Standards

Related Pathways

Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C1OC2(C3=C(OC4=C2C=CC(O)=C4O)C(O)=C(O)C=C3)C5=C1C=CC=C5

Molecular Formula

C20H12O7

Molecular Weight

364.31

References & Citations

[1]Sanz G, et al, Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10 (1) :541. |[2]Kuroyanagi G, Hioki T, Matsushima-Nishiwaki R, Kozawa O, Tokuda H. Gallein increases the fibroblast growth factor 2-elicited osteoprotegerin synthesis in osteoblasts. Biochim Biophys Acta Gen Subj. 2024 Aug;1868 (8) :130635. |[3]Alarabi AB, et al. The G-protein βγ subunits regulate platelet function. Life Sci. 2020 Dec 1;262:118481.