Fursultiamine (Standard)
Fursultiamine (Standard) is the analytical standard of Fursultiamine. This product is intended for research and analytical applications. Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1 deficiency, osteoarthritis (OA) and cancer research[1][2].
Product Specifications
CAS Number
804-30-8
UNSPSC
12352005
Target
Ferroportin; Mitochondrial Metabolism; NF-κB; Reference Standards; VEGFR
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Smiles
O=CN(CC1=CN=C(C)N=C1N)/C(C)=C(SSCC2OCCC2)\CCO
Molecular Formula
C17H26N4O3S2
Molecular Weight
398.54
References & Citations
[1]Kobayashi T, et al. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflamm Res. 2005 Jun;54 (6) :249-55.|[2]Xiao-Yi Xiong, et al. Toll-Like Receptor 4/MyD88-Mediated Signaling of Hepcidin Expression Causing Brain Iron Accumulation, Oxidative Injury, and Cognitive Impairment After Intracerebral Hemorrhage. Circulation. 2016 Oct 4;134 (14) :1025-1038.|[3]Wang J, et al., Hepcidin Downregulation Correlates With Disease Aggressiveness And Immune Infiltration in Liver Cancers. Front Oncol. 2021 Jun 30;11:714756.|[4]Do JY, et al., Fursultiamine Alleviates Choroidal Neovascularization by Suppressing Inflammation and Metabolic Reprogramming. Invest Ophthalmol Vis Sci. 2020 Oct 1;61 (12) :24.|[5]Fursultiamine alleviates choroidal neovascularization by suppressing inflammation and metabolic reprogramming
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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