Fursultiamine (Standard)

Fursultiamine (Standard) is the analytical standard of Fursultiamine. This product is intended for research and analytical applications. Fursultiamine is a vitamin B1 derivative, has anti-nociceptive and antineoplastic activity. Fursultiamine can be used for vitamin B1 deficiency, osteoarthritis (OA) and cancer research[1][2].

Product Specifications

CAS Number

[804-30-8]

UNSPSC

12352005

Target

Ferroportin; Mitochondrial Metabolism; NF-κB; Reference Standards; VEGFR

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB; Others; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Smiles

O=CN(CC1=CN=C(C)N=C1N)/C(C)=C(SSCC2OCCC2)\CCO

Molecular Formula

C17H26N4O3S2

Molecular Weight

398.54

References & Citations

[1]Kobayashi T, et al. Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflamm Res. 2005 Jun;54 (6) :249-55.|[2]Xiao-Yi Xiong, et al. Toll-Like Receptor 4/MyD88-Mediated Signaling of Hepcidin Expression Causing Brain Iron Accumulation, Oxidative Injury, and Cognitive Impairment After Intracerebral Hemorrhage. Circulation. 2016 Oct 4;134 (14) :1025-1038.|[3]Wang J, et al., Hepcidin Downregulation Correlates With Disease Aggressiveness And Immune Infiltration in Liver Cancers. Front Oncol. 2021 Jun 30;11:714756.|[4]Do JY, et al., Fursultiamine Alleviates Choroidal Neovascularization by Suppressing Inflammation and Metabolic Reprogramming. Invest Ophthalmol Vis Sci. 2020 Oct 1;61 (12) :24.|[5]Fursultiamine alleviates choroidal neovascularization by suppressing inflammation and metabolic reprogramming