Piperacillin (hydrate)
Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin hydrate is most commonly used in combination with the β-lactamase inhibitor Tazobactam[2][3].
Product Specifications
CAS Number
66258-76-2
Product Name Alternative
Pipracil (hydrate)
UNSPSC
12352005
Hazard Statement
H317-H412
Target
Antibiotic; Bacterial; Beta-lactamase; Penicillin-binding protein (PBP)
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Smiles
O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3C(C(N(CC)CC3)=O)=O)=O)C4=CC=CC=C4)=O)N1C2=O)O.O
Molecular Formula
C23H29N5O8S
Molecular Weight
535.57
Precautions
P261-P272-P273-P280-P302+P352-P362+P364-P501
References & Citations
[1]Fu KP, et al. Piperacillin, a new penicillin active against many bacteria resistant to other penicillins. Antimicrob Agents Chemother. 1978, 13 (3) :358-67. |[2]Bodey GP, et al. Piperacillin: In Vitro Evaluation. Antimicrob Agents Chemother. 1978, 14 (1) :78-87. |[3]Harada Y, et al. In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae. Clin Microbiol Infect. 2014, 20 (11) :O831-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
Frequently Asked Questions
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