Bromfenac (sodium) (Standard)
Bromfenac (sodium) (Standard) is the analytical standard of Bromfenac (sodium) . This product is intended for research and analytical applications. Bromfenac sodium is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. Bromfenac sodium can be used in ocular inflammation research[1].
Product Specifications
UNSPSC
12352100
Hazard Statement
H301
Target
COX; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Infection; Inflammation/Immunology
Smiles
O=C(O[Na])CC1=CC=CC(C(C2=CC=C(Br)C=C2)=O)=C1N
Molecular Formula
C15H11BrNNaO3
Molecular Weight
356.15
Precautions
P264-P270-P405-P501
References & Citations
[1]Tetsuo Kida, et al. Pharmacokinetics and efficacy of topically applied nonsteroidal anti-inflammatory drugs in retinochoroidal tissues in rabbits. PLoS One. 2014 May 5;9 (5) :e96481.|[2]Xiaobo Zhang, et al. Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification. Bioact Mater. 2021 Jul 23;9:343-357.|[3]Nolan JC, et, al. The topical anti-inflammatory and analgesic properties of bromfenac in rodents. Agents Actions. 1988 Aug; 25 (1-2) : 77-85.|[4]Kaevalin Lekhanont, et al. Effects of topical anti-inflammatory agents in a botulinum toxin B-induced mouse model of keratoconjunctivitis sicca. J Ocul Pharmacol Ther. 2007 Feb;23 (1) :27-34.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1888AR/
Scientific Category
Reference Standards
CAS Number
[91714-93-1]
Available Sizes
Curated Selection
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