Quinidine-13C, d2 (hydrochloride)
Quinidine-13C, d2 hydrochloride is the deuterium and 13C-labeled Quinidine. Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K+ channel with an IC50 of 19.9 μM[1][2].
Product Specifications
UNSPSC
12352005
Target
Isotope-Labeled Compounds; Parasite; Potassium Channel
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Others
Field of Research
Infection; Cardiovascular Disease
Smiles
C=C[C@H]1C[N@](CC[C@H]1C2)[C@@]2([H])[13C]([2H])(O[2H])C3=CC=NC4=CC=C(OC)C=C34.Cl
Molecular Formula
C19 13CH23D2ClN2O2
Molecular Weight
363.88
References & Citations
[1]Wrighton DC, et al. Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium. Br J Pharmacol. 2015 Sep;172 (17) :4355-63.|[2]Cheng KI, et al. Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses. J Anesth. 2014 Aug;28 (4) :559-68.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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