Quinidine-13C, d2 (hydrochloride)

Quinidine-13C, d2 hydrochloride is the deuterium and 13C-labeled Quinidine (HY-B1302) . Quinidine hydrochloride monohydrate is an anti-arrythmic agent which is also a potent blocker of K+ channel with an IC50 of 19.9 μM[1][2].

Product Specifications

UNSPSC

12352005

Target

Isotope-Labeled Compounds; Parasite; Potassium Channel

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Others

Field of Research

Infection; Cardiovascular Disease

Smiles

C=C[C@H]1C[N@](CC[C@H]1C2)[C@@]2([H])[13C]([2H])(O[2H])C3=CC=NC4=CC=C(OC)C=C34.Cl

Molecular Formula

C19 13CH23D2ClN2O2

Molecular Weight

363.88

References & Citations

[1]Wrighton DC, et al. Mechanism of inhibition of mouse Slo3 (KCa 5.1) potassium channels by quinine, quinidine and barium. Br J Pharmacol. 2015 Sep;172 (17) :4355-63.|[2]Cheng KI, et al. Application of quinidine on rat sciatic nerve decreases the amplitude and increases the latency of evoked responses. J Anesth. 2014 Aug;28 (4) :559-68.