Pyridoxamine 5′-phosphate (Standard)

Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium) . This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19[1][2][3].

Product Specifications

CAS Number

[529-96-4]

UNSPSC

12352005

Target

Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Smiles

O=P(O)(OCC1=CN=C(C)C(O)=C1CN)O

Molecular Formula

C8H13N2O5P

Molecular Weight

248.17

References & Citations

[1]Seo JH, et, al. Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases. Biotechnol Bioeng. 2011 Feb;108 (2) :253-63.