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Methdilazine (hydrochloride) (Standard)

Thioridazine (Standard) is the analytical standard of Thioridazine. This product is intended for research and analytical applications. Thioridazine, an antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) [1][2][3][4].

Product Specifications

CAS Number

[1229-35-2]

UNSPSC

12352005

Target

Antibiotic; Bacterial; Histamine Receptor; Reference Standards

Related Pathways

Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Infection

Smiles

CN(CC1)CC1CN2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl

Molecular Formula

C18H21ClN2S

Molecular Weight

332.89

References & Citations

[1]A N Chakrabarty, et al. Antimycobacterial activity of methdilazine (Md), an antimicrobic phenothiazine. APMIS. 1993 Jun;101 (6) :449-54. |[2]Noton K Dutta, et al. Activity of the phenothiazine methdilazine alone or in combination with isoniazid or streptomycin against Mycobacterium tuberculosis in mice. J Med Microbiol. 2009 Dec;58 (Pt 12) :1667-1668.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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