Chlorphenoxamine (hydrochloride)
Chlorphenoxamine hydrochloride, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine hydrochloride inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine hydrochloride shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine hydrochloride is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease[1][2][3][4][5].
Product Specifications
CAS Number
562-09-4
UNSPSC
12352005
Hazard Statement
H302
Target
Filovirus; Histamine Receptor; Parasite; SARS-CoV
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Infection; Neurological Disease; Inflammation/Immunology
Smiles
CC(C1=CC=CC=C1)(C2=CC=C(Cl)C=C2)OCCN(C)C.Cl
Molecular Formula
C18H23Cl2NO
Molecular Weight
340.29
Precautions
P264-P270-P330-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Frequently Asked Questions
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