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Thiacetazone (Standard)

Thiacetazone (Standard) is the analytical standard of Thiacetazone. This product is intended for research and analytical applications. Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL[1].

Product Specifications

CAS Number

104-06-3

Product Name Alternative

Thioacetazone (Standard) ; Amithiozone (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CC(NC1=CC=C(/C=N/NC(N)=S)C=C1)=O

Molecular Formula

C10H12N4OS

Molecular Weight

236.29

References & Citations

[1]J L Stigliani, et al. New Insights Into the Chemical Behavior of S-oxide Derivatives of Thiocarbonyl-Containing Antitubercular Drugs and the Influence on Their Mechanisms of Action and Toxicity. Ann Pharm Fr. 2019 Mar;77 (2) :126-135.|[2] P Khanna, et al. Characteristics of a Cytosolic Arylacylamidase Metabolizing Thiacetazone. J Pharmacol Exp Ther. 1992 Sep;262 (3) :1225-31.|[3]Anuradha Alahari, et al. Thiacetazone, an Antitubercular Drug That Inhibits Cyclopropanation of Cell Wall Mycolic Acids in Mycobacteria. PLoS One. 2007 Dec 19;2 (12) :e1343.|[4]C A Peloquin, et al. Pharmacokinetic Evaluation of Thiacetazone. Pharmacotherapy. Sep-Oct 1996;16 (5) :735-41.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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