Ethoxzolamide (Standard)

Ethoxzolamide (Standard) is the analytical standard of Ethoxzolamide. This product is intended for research and analytical applications. Ethoxzolamide is a carbonic anhydrase inhibitor with Ki of 1 nM.

Product Specifications

CAS Number

[452-35-7]

UNSPSC

12352100

Target

Bacterial; Carbonic Anhydrase; Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Infection; Inflammation/Immunology

Smiles

O=S(C1=NC2=CC=C(OCC)C=C2S1)(N)=O

Molecular Formula

C9H10N2O3S2

Molecular Weight

258.32

References & Citations

[1]Maren TH, et al. Relations among IOP reduction, ocular disposition and pharmacology of the carbonic anhydrase inhibitor ethoxzolamide. Exp Eye Res. 1992 Jul;55 (1) :73-9.|[2]Benjamin K. Johnson, et al. The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits theMycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence. Antimicrob Agents Chemother. 2015 Aug; 59 (8) : 4436–4445.|[3]Song Gao, et al. Development and validation of an UPLC-MS/MS method for the quantification of ethoxzolamide in plasma and bioequivalent buffers: Applications to absorption, brain distribution, and pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1; 0: 54–59.