Imidapril (hydrochloride) (Standard)

Imidapril (hydrochloride) (Standard) is the analytical standard of Imidapril (hydrochloride) . This product is intended for research and analytical applications. Imidapril hydrochloride (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril hydrochloride suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril hydrochloride can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research[1][2].

Product Specifications

CAS Number

[89396-94-1]

UNSPSC

12352100

Target

Angiotensin-converting Enzyme (ACE) ; MMP; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Cardiovascular Disease

Smiles

O=C([C@H](CN1C)N(C([C@@H](N[C@H](C(OCC)=O)CCC2=CC=CC=C2)C)=O)C1=O)O.[H]Cl

Molecular Formula

C20H28ClN3O6

Molecular Weight

441.91

References & Citations

[1]Robinson DM, et al. Imidapril: a review of its use in essential hypertension, Type 1 diabetic nephropathy and chronic heart failure. Drugs. 2007;67 (9) :1359-78.|[2]Yamamoto D, et al. Molecular mechanism of imidapril for cardiovascular protection via inhibition of MMP-9. J Mol Cell Cardiol. 2007 Dec;43 (6) :670-6.