Perindoprilat (Standard)
Perindoprilat (Standard) is the analytical standard of Perindoprilat. This product is intended for research and analytical applications. Perindoprilat (S 9780) is an angiotensin-converting enzyme (ACE) inhibitor with the IC50 value ranging from 1.5 to 3.2 nM. Perindoprilat can be used in hypertension research[1][2].
Product Specifications
CAS Number
95153-31-4
UNSPSC
12352100
Hazard Statement
H302, H312, H332
Target
Angiotensin-converting Enzyme (ACE) ; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Purity
99.61
Smiles
O=C([C@H]1N(C([C@@H](N[C@H](C(O)=O)CCC)C)=O)[C@@]2([H])CCCC[C@@]2([H])C1)O
Molecular Formula
C17H28N2O5
Molecular Weight
340.41
Precautions
H302, H312, H332
References & Citations
[1]Perindopril. Expert Opin Pharmacother. 2006 Jan;7 (1) :63-71.|[2]Angiotensin-converting enzyme (ACE) inhibitors have different selectivity for bradykinin binding sites of human somatic ACE. Eur J Pharmacol. 2007 Dec 22;577 (1-3) :1-6.|[3]Izabella Z A Pawluczyk, et al. The role of bradykinin in the antifibrotic actions of perindoprilat on human mesangial cells. Kidney Int. 2004 Apr;65 (4) :1240-51.|[4]X-Z Wang, et al. Perindopril inhibits myocardial apoptosis in mice with acute myocardial infarction through TLR4/NF-κB pathway. Eur Rev Med Pharmacol Sci. 2019 Aug;23 (15) :6672-6682.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
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