Ractopamine-d3 (hydrochloride)

Ractopamine-d3 (LY031537-d3) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421) . Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with Kd values of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs[1][2][3].

Product Specifications

CAS Number

[1219794-72-5]

Product Name Alternative

LY031537-d3

UNSPSC

12352005

Hazard Statement

H302+H332-H317

Target

Adrenergic Receptor; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1CCC(C)NC([2H])([2H])C(C2=CC=C(C=C2)O)([2H])O.Cl

Molecular Formula

C18H21D3ClNO3

Molecular Weight

340.86

Precautions

P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91 (9) :4180-4187.|[3]Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120 (12) :1677-1683. |[4] S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28-E32.