Ractopamine-d9 (hydrochloride)

Ractopamine-d9 (LY031537-d9) hydrochloride is the deuterium labeled Ractopamine hydrochloride (HY-B1421) . Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with Kd values of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs[1][2][3].

Product Specifications

Product Name Alternative

LY031537-d9

UNSPSC

12352005

Target

Adrenergic Receptor; Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

OC(C([2H])([2H])NC(C([2H])([2H])[2H])([2H])C([2H])([2H])CC1=CC=C(O)C=C1)([2H])C2=CC=C(O)C=C2.Cl

Molecular Formula

C18H15D9ClNO3

Molecular Weight

346.90

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91 (9) :4180-4187.|[3]Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120 (12) :1677-1683. |[4] S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28-E32.