Tazobactam-15N, d2

Tazobactam-15N, d2 (CL-298741-15N, d2) is 15N and deuterium labeled Tazobactam. Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research[1][2].

Product Specifications

Product Name Alternative

CL-298741-15N, d2; YTR-830H-15N, d2

UNSPSC

12352005

Target

Antibiotic; Bacterial; Beta-lactamase; Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Smiles

C[C@@]1([C@@H]([15N]2[C@](CC2=O)([H])S1(=O)=O)C(O)=O)C([2H])([2H])N3C=CN=N3

Molecular Formula

C10H10D2N3 15NO5S

Molecular Weight

303.30

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Harada Y, et, al. In vitro and in vivo activities of piperacillin-tazobactam and meropenem at different inoculum sizes of ESBL-producing Klebsiella pneumoniae. Clin Microbiol Infect. 2014 Nov;20 (11) :O831-9.|[3]Higashitani F, et, al. Inhibition of beta-lactamases by tazobactam and in-vitro antibacterial activity of tazobactam combined with piperacillin. J Antimicrob Chemother. 1990 Apr;25 (4) :567-74.