Fenclonine (Standard)

Fenclonine (Standard) is the analytical standard of Fenclonine. This product is intended for research and analytical applications. Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research[1][2][3].

Product Specifications

CAS Number

[7424-00-2]

UNSPSC

12352100

Target

Reference Standards; Tryptophan Hydroxylase

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Neurological Disease

Smiles

NC(CC1=CC=C(Cl)C=C1)C(O)=O

Molecular Formula

C9H10ClNO2

Molecular Weight

199.64

References & Citations

[1]M Jouvet. Sleep and serotonin: an unfinished story. Neuropsychopharmacology. 1999 Aug;21 (2 Suppl) :24S-27S.|[2]A K Sanyal, et al. Prostaglandins: antinociceptive effect of prostaglandin E1 in the rat. Clin Exp Pharmacol Physiol. 1977 May-Jun;4 (3) :247-55.|[3]Shyamshree S S Manna, et al. Paracetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetine. Behav Pharmacol. 2015 Apr;26 (3) :268-81.|[4]Zheng Y, et al. In silico Analysis and Experimental Validation of Lignan Extracts from Kadsura longipedunculata for Potential 5-HT1AR Agonists. PLoS One. 2015 Jun 15;10 (6) :e0130055.