Oxyphenbutazone (Standard)

Oxyphenbutazone (Standard) is the analytical standard of Oxyphenbutazone. This product is intended for research and analytical applications. Oxyphenbutazone is a Phenylbutazone (HY-B0230) metabolite, with anti-inflammatory effect. Oxyphenbutazone is an orally active non-selective COX inhibitor. Oxyphenbutazone selectively kills non-replicating Mycobaterium tuberculosis[1][2].

Product Specifications

CAS Number

[129-20-4]

UNSPSC

12352100

Target

Bacterial; COX; Reference Standards

Related Pathways

Anti-infection; Immunology/Inflammation; Others

Field of Research

Infection; Inflammation/Immunology

Smiles

O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=C(O)C=C3)C1=O

Molecular Formula

C19H20N2O3

Molecular Weight

324.37

References & Citations

[1]Saleem S, et al. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway. Mol Cell Biochem. 2018 Jul;444 (1-2) :187-196.|[2]Gold B, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A. 2012 Oct 2;109 (40) :16004-11.