Chlortetracycline-d6 (hydrochloride)

Chlortetracycline-d6 (hydrochloride) is the deuterium labeled Chlortetracycline hydrochloride. Chlortetracycline hydrochloride (7-Chlorotetracycline hydrochloride) is a specific and potent calcium ionophore antibiotic, inhibits binding of aminoacyl-tRNA to ribosomes.

Product Specifications

Product Name Alternative

7-Chlorotetracycline-d6 (hydrochloride)

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

O[C@]12[C@](C[C@@]3([H])C(C(C4=C(O)C=CC(Cl)=C4[C@]3(O)C)=O)=C2O)([H])[C@@H](C(O)=C(C1=O)C(N)=O)N(C([2H])([2H])[2H])C([2H])([2H])[2H].Cl

Molecular Formula

C22H18D6Cl2N2O8

Molecular Weight

521.38

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Elmund GK, et al. Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste. Bull Environ Contam Toxicol. 1971 Mar-Apr;6 (2) :129-32.|[3]Saling PM, et al. Mouse gamete interactions during fertilization in vitro. Chlortetracycline as a fluorescent probe for the mouse sperm acrosome reaction. J Cell Biol. 1979 Dec;83 (3) :544-55.