Foscarnet (sodium) (Standard)

Foscarnet (sodium) (Standard) is the analytical standard of Foscarnet (sodium) . This product is intended for research and analytical applications. Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3].

Product Specifications

CAS Number

[63585-09-1]

UNSPSC

12352100

Target

DNA/RNA Synthesis; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Infection

Smiles

O=P(O[Na])(O[Na])C(O[Na])=O

Molecular Formula

CNa3O5P

Molecular Weight

191.95

References & Citations

[1]Manischewitz JF, et al. Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro.Antimicrob Agents Chemother. 1990 Feb;34 (2) :373-5.|[2]Oberg B, et al. Antiviral effects of phosphonoformate (PFA, foscarnet sodium) .Pharmacol Ther. 1982;19 (3) :387-415.|[3]Hakki M, et al. Moving Past Ganciclovir and Foscarnet: Advances in CMV Therapy.Curr Hematol Malig Rep. 2020 Jan 24.