Metacetamol
Metacetamol (AMAP) is a non-hepatotoxic analog of acetaminophen (APAP) . Metacetamol increases glutathione (GSH) in PHH and causes mitochondrial damage. Metacetamol increases total JNK in PHH cell [1].
Product Specifications
CAS Number
621-42-1
Product Name Alternative
AMAP
UNSPSC
12352005
Hazard Statement
H315, H319
Target
JNK; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Field of Research
Metabolic Disease
Purity
99.97
Smiles
CC(NC1=CC=CC(O)=C1)=O
Molecular Formula
C8H9NO2
Molecular Weight
151.16
Precautions
H315, H319
References & Citations
[1]Yuchao Xie, et al. Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP) -induced hepatotoxicity in primary human hepatocytes. Toxicol Appl Pharmacol. 2015, 289, 2.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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