Lithium citrate (tetrahydrate)

Lithium citrate (Litarex) tetrahydrate is a natural preservative and food tartness enhancer. Lithium citrate tetrahydrate induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Lithium citrate tetrahydrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Lithium citrate tetrahydrate is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries[1][2][3][4].

Product Specifications

CAS Number

[6080-58-6]

Product Name Alternative

Litarex (tetrahydrate)

UNSPSC

12352200

Hazard Statement

H302

Target

Apoptosis; Bacterial; Endogenous Metabolite

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Concentration

10mM

Purity

98.0

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(CC(C(O[Li])=O)(O)CC(O[Li])=O)O[Li].O.O.O.O

Molecular Formula

C6H13Li3O11

Molecular Weight

281.98

Precautions

H302

References & Citations

[1]Chen X, et al. Study on injury effect of food additive citric acid on liver tissue in mice. Cytotechnology. 2014 Mar;66 (2) :275-82.|[2]Chen X, Lv Q, Liu Y, Deng W. Effects of the food additive, citric acid, on kidney cells of mice. Biotech Histochem. 2015 Jan;90 (1) :38-44. |[3]Ying TH, et al. Citric acid induces cell-cycle arrest and apoptosis of human immortalized keratinocyte cell line (HaCaT) via caspase- and mitochondrial-dependent signaling pathways. Anticancer Res. 2013 Oct;33 (10) :4411-20. |[4]Ciriminna R, et al. Citric acid: emerging applications of key biotechnology industrial product. Chem Cent J. 2017 Mar 8;11:22.