Promazine-d6 (hydrochloride)
Promazine-d6 (hydrochloride) (Romtiazin-d6 (hydrochloride) ) is deuterium labeled Promazine (hydrochloride) . Promazine (Romtiazin) hydrochloride is an antipsychotic and a dopamine receptor D2 antagonist. Promazine hydrochloride inhibits dopaminergic neurotransmission[1][2].
Product Specifications
CAS Number
1246819-33-9
Product Name Alternative
Romtiazin-d6 (hydrochloride) ; Ampazine-d6 (hydrochloride)
UNSPSC
12352005
Target
Dopamine Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
[2H]C([2H])([2H])N(C([2H])([2H])[2H])CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl
Molecular Formula
C17H15D6ClN2S
Molecular Weight
326.92
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Gareri P, et al. Conventional and atypical antipsychotics in the elderly : a review. Clin Drug Investig. 2003;23 (5) :287-322. |[3]Myers PR, et al. Characterization of a depolarizing dopamine response in a vertebrate neuronal somatic cell hybrid. J Cell Physiol. 1977;91 (1) :103-118. |[4]Tatsumi M, et al. Pharmacological profile of neuroleptics at human monoamine transporters. Eur J Pharmacol. 1999;368 (2-3) :277-283.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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