Oxeladin
Oxeladin is an orally active and brain-penetrant cough suppressant as well as a selective sigma 1 receptor agonist (Ki = 25 nM) . Oxeladin can be used for pulmonary diseases and stroke research[1][2].
Product Specifications
CAS Number
468-61-1
UNSPSC
12352005
Hazard Statement
H301-H311-H331
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease; Cardiovascular Disease; Inflammation/Immunology
Smiles
O=C(OCCOCCN(CC)CC)C(CC)(CC)C1=CC=CC=C1
Molecular Formula
C20H33NO3
Molecular Weight
335.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
References & Citations
[1]Schreihofer DA, et al. Treatment of Stroke at a Delayed Timepoint with a Repurposed Drug Targeting Sigma 1 Receptors. Transl Stroke Res. 2023. Epub ahead of print. |[2]Dalwadi DA, et al. Brain-derived neurotrophic factor for high-throughput evaluation of selective Sigma-1 receptor ligands. J Pharmacol Toxicol Methods. 2022;113:107129.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Sigma 1 Receptor
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