Lofexidine (hydrochloride) (Standard)

Lofexidine (hydrochloride) (Standard) is the analytical standard of Lofexidine (hydrochloride) . This product is intended for research and analytical applications. Lofexidine (hydrochloride) is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal[1][2].

Product Specifications

CAS Number

[21498-08-8]

UNSPSC

12352100

Target

Adrenergic Receptor; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Smiles

CC(C1=NCCN1)OC2=C(Cl)C=CC=C2Cl.[H]Cl

Molecular Formula

C11H13Cl3N2O

Molecular Weight

295.59

References & Citations

[1]Vartak AP, et al. The preclinical discovery of lofexidine for the treatment of opiate addiction. Expert Opin Drug Discov. 2014 Nov;9 (11) :1371-7.|[2]Gish EC, et al. Lofexidine, an {alpha}2-receptor agonist for opioid detoxification. Ann Pharmacother. 2010 Feb;44 (2) :343-51.