Thioridazine-d3 2-Sulfone
Thioridazine-d3 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs) [1][2][3][4].
Product Specifications
CAS Number
1329652-09-6
UNSPSC
12352005
Target
5-HT Receptor; Apoptosis; Autophagy; Bacterial; Dopamine Receptor; Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer; Infection; Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(CC1N(C([2H])([2H])[2H])CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(C)(=O)=O)C3
Molecular Formula
C21H23D3N2O2S2
Molecular Weight
405.59
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
D3 Receptor
Available Sizes
Frequently Asked Questions
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