Azaserine (Standard)

Bamethan (hemisulfate) (Standard) is the analytical standard of Bamethan (hemisulfate) . This product is intended for research and analytical applications. Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.

Product Specifications

CAS Number

[115-02-6]

Product Name Alternative

CI-337 (Standard) ; O-Diazoacetyl-L-serine (Standard) ; P-165 (Standard)

UNSPSC

12352211

Target

Antibiotic; Bacterial; DNA/RNA Synthesis; Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Field of Research

Cancer; Infection

Smiles

N[C@@H](COC(C=[N+]=[N-])=O)C(O)=O

Molecular Formula

C5H7N3O4

Molecular Weight

173.13

References & Citations

[1]Longnecker DS, Curphey TJ. Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res. 1975 Aug;35 (8) :2249-58.|[2]Shigemichi GUNJI, et al. Screening of Antifungal Antibiotics According to Activities Inducing Morphological Abnormalities. Agric. Biol Chem., 47 (9), 2061-2069, 1983.|[3]Williams MV, Tritz GJ. Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal. J Antimicrob Chemother. 1977 Jan;3 (1) :65-77.|[4]Catane R, et al. Azaserine, DON, and azotomycin: three diazo analogs of L-glutamine with clinical antitumor activity. Cancer Treat Rep. 1979 Jun;63 (6) :1033-8. |[5]Lyons SD, et al. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265 (19) :11377-81.